Searchable abstracts of presentations at key conferences in endocrinology

ea0086p213 | Metabolism, Obesity and Diabetes | SFEBES2022

Differentially expressed genes in insulin resistant macrophages are shared across multiple diabetes associated morbidities

Goodhew Katie , Grammatopoulos Kyriakos , Jackson Amy , Makahamadze Ayanteh , Pineda-Torra Ines , Yuldasheva Nadira , Kearney Mark , Gage Matthew

Authors 1-4 contributed equally to this work.Background: Insulin resistance is the central defining feature of type 2 diabetes and increases with age. People with type 2 diabetes are at an increased risk of cardiovascular disease, non-alcoholic fatty liver disease (NAFLD), Alzheimer’s disease and arthritis. Macrophages are phagocytotic leukocytes which play a central role in the development of type 2 diabetes and the chronic inflammatory di...